4718

• Gene Symbol: TLR3
• Gene Name: toll like receptor 3
• Gene Aliases: CD283, IIAE2
• Chromosome Location: Chr.4: 186069155 - 186086724 on Build GRCh38
• UniGene ID: Hs.657724
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TLR3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003265.2	NP_003256.1	5	2714
	XM_017008577.1	XP_016864066.1	3	2404
GenBank mRNA	AB445631.1	-	4	2613
	AK302143.1	-	3	2192
	AK314208.1	-	5	2713
	BC043204.2	-	2	2696
	BC094737.1	-	5	2713	30531515
	BC096333.1	-	5	2691	40008349
	BC096334.3	-	5	2691	40008350
	BC096335.1	-	5	2691	40008351
	DQ445682.1	-	5	2684
	U88879.1	-	5	2686

More Information

Gene Ontology Categories:

Process(es)

toll-like receptor signaling pathway
microglial cell activation involved in immune response
regulation of dendritic cell cytokine production
MyD88-independent toll-like receptor signaling pathway
inflammatory response
hyperosmotic response
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
I-kappaB phosphorylation
male gonad development
detection of virus
positive regulation of gene expression
positive regulation of chemokine production
positive regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor signaling pathway
negative regulation of MyD88-independent toll-like receptor signaling pathway
toll-like receptor 3 signaling pathway
positive regulation of type III interferon production
cellular response to interferon-beta
TRIF-dependent toll-like receptor signaling pathway
cellular response to drug
positive regulation of NF-kappaB import into nucleus
defense response to bacterium
positive regulation of apoptotic process
response to exogenous dsRNA
positive regulation of interferon-gamma biosynthetic process
positive regulation of chemokine biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
positive regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
defense response to virus
necroptotic process
cellular response to mechanical stimulus
cellular response to interferon-gamma
cellular response to exogenous dsRNA
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
necroptotic signaling pathway

Function(s)

double-stranded RNA binding
receptor activity
transmembrane signaling receptor activity
protein binding
identical protein binding