47824

• Gene Symbol: Gck
• Gene Name: glucokinase
• Gene Aliases: GLUKA, RNGK2
• Chromosome Location: Chr.14: 86149146 - 86191576 on Build Rnor_6.0
• UniGene ID: Rn.10447
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gck
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001270849.1	NP_001257778.1	3	348
	NM_001270850.1	NP_001257779.1	2	125
	NM_012565.2	NP_036697.1	2	197
	XM_006251179.2	XP_006251241.1	2	1042
GenBank mRNA	J04218.1	-	2	156
	KJ026953.1	-	2	89
	M25807.1	-	2	125
	M58759.1	-	2	579
	X53588.1	-	2	180
	X53589.1	-	3	348

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010292, L38990, BC011139, AK142698, M58755.

Panther Classification:

Molecular Function -

kinase

Gene Ontology Categories:

Process(es)

cellular glucose homeostasis
glycogen biosynthetic process
fructose 2,6-bisphosphate metabolic process
glucose metabolic process
glycolytic process
NADP metabolic process
positive regulation of cytosolic calcium ion concentration
response to glucose
second-messenger-mediated signaling
positive regulation of insulin secretion
negative regulation of epinephrine secretion
cellular response to insulin stimulus
cellular response to glucose starvation
positive regulation of phosphorylation
glucose homeostasis
regulation of potassium ion transport
cellular response to leptin stimulus
negative regulation of gluconeogenesis
positive regulation of glycogen biosynthetic process
positive regulation of glycolytic process
carbohydrate phosphorylation
regulation of insulin secretion
glucose 6-phosphate metabolic process
detection of glucose
lipid homeostasis
calcium ion import

Function(s)

magnesium ion binding
glucokinase activity
protein binding
ATP binding
glucose binding
fructokinase activity
mannokinase activity
protein phosphatase binding
ADP binding