4800

• Gene Symbol: BECN1
• Gene Name: beclin 1
• Gene Aliases: ATG6, VPS30, beclin1
• Chromosome Location: Chr.17: 42810132 - 42824316 on Build GRCh38
• UniGene ID: Hs.716464
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BECN1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001313998.1	NP_001300927.1	2, 3	292
	NM_001313999.1	NP_001300928.1	1, 2	130
	NM_001314000.1	NP_001300929.1	2, 3	292
	NM_003766.4	NP_003757.1	2, 3	314
	XM_005257759.2	XP_005257816.1	2, 3	236
	XM_005257760.3	XP_005257817.1	2, 3	236
	XM_011525421.2	XP_011523723.1	2, 3	236
	XM_017025262.1	XP_016880751.1	2, 3	309
	XM_017025263.1	XP_016880752.1	2, 3	309
	XM_017025264.1	XP_016880753.1	2, 3	309
GenBank mRNA	AF077301.1	-	1, 2	128
	AF139131.1	-	2, 3	248
	AK223411.1	-	2, 3	256
	AK298619.1	-	2, 3	264
	AK299616.1	-	2, 3	266
	AK312651.1	-	2, 3	239
	BC010276.1	-	2, 3	261	2901072
	BX647788.1	-	2, 3	255
	DC296896.1	-	2, 3	291
	DC354547.1	-	2, 3	314
	KC776730.1	-	1, 2	128

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053739, NM_001034117, BC074011, AY033824, CB788828, and others.
This siRNA also targets the following transcripts in Mouse: NM_019584, AK083800, AF077302, AK050329, BC005770, and others.

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

autophagosome assembly
cytokinesis
response to hypoxia
autophagy
apoptotic process
cellular defense response
cellular response to nitrogen starvation
lysosome organization
mitotic metaphase plate congression
negative regulation of cell proliferation
positive regulation of autophagy
positive regulation of phosphatidylinositol 3-kinase signaling
macroautophagy
positive regulation of macroautophagy
CVT pathway
regulation of cytokinesis
receptor catabolic process
response to vitamin E
cellular response to glucose starvation
response to drug
negative regulation of apoptotic process
engulfment of apoptotic cell
nucleophagy
late endosome to vacuole transport
neuron development
beta-amyloid metabolic process
regulation of catalytic activity
defense response to virus
negative regulation of cell death
cellular response to aluminum ion
cellular response to epidermal growth factor stimulus
mitophagy in response to mitochondrial depolarization
positive regulation of attachment of mitotic spindle microtubules to kinetochore
positive regulation of mitophagy
negative regulation of reactive oxygen species metabolic process

Function(s)

protein binding
ubiquitin protein ligase binding
phosphatidylinositol 3-kinase binding