48134

Gene Symbol:

Nos2 LOC497963

Gene Name:

nitric oxide synthase 2, inducible

similar to Nitric oxide synthase, inducible (NOS type II) (Inducible NO synthase) (Inducible NOS) (iNOS)

Gene Aliases:

Nos2a, iNos

-

Chromosome Location:

Chr.10: 66188290 - 66221621 on Build Rnor_6.0

Chromosome Location:

Chr.10: 66282166 - 66313364 on Build Rnor_6.0

UniGene ID:

Rn.10400

-

Species:

Rat

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Nos2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012611.3	NP_036743.3		702
GenBank mRNA	AY211532.1	-		513
	D12520.1	-		702
	D14051.1	-		532
	D44591.1	-		533
	L12562.1	-		614
	U03699.1	-		515
	U26686.1	-		512
	X76881.1	-		697

Gene Symbol: LOC497963
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_006246949.2	XP_006247011.1		567

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010927, M92649, AY090567, M87039, AF065923, and others.

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

ovulation from ovarian follicle
response to hypoxia
endothelial cell proliferation
blood vessel remodeling
arginine catabolic process
superoxide metabolic process
nitric oxide biosynthetic process
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
nitric oxide mediated signal transduction
aging
regulation of heart contraction
regulation of blood pressure
response to mechanical stimulus
response to hormone
negative regulation of gene expression
response to activity
glycoside metabolic process
peptidyl-cysteine S-nitrosylation
cGMP-mediated signaling
positive regulation of guanylate cyclase activity
response to estradiol
response to lipopolysaccharide
response to tumor necrosis factor
intracellular signal transduction
response to immobilization stress
wound healing
regulation of cell proliferation
negative regulation of protein catabolic process
defense response to bacterium
positive regulation of apoptotic process
negative regulation of blood pressure
regulation of protein kinase activity
positive regulation of vasodilation
retinoic acid receptor signaling pathway
regulation of insulin secretion
defense response to Gram-negative bacterium
positive regulation of killing of cells of other organism
oxidation-reduction process
cellular response to lipopolysaccharide
cellular response to lithium ion
cellular response to vitamin D
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to redox state
response to dexamethasone

Function(s)

actin binding
NADPH-hemoprotein reductase activity
nitric-oxide synthase activity
receptor binding
iron ion binding
calmodulin binding
beta-catenin binding
cAMP-dependent protein kinase regulator activity
FMN binding
amino acid binding
protein kinase binding
heme binding
tetrahydrobiopterin binding
arginine binding
protein homodimerization activity
cadherin binding
flavin adenine dinucleotide binding
NADP binding
nitric-oxide synthase binding
Hsp90 protein binding