4832

• Gene Symbol: PHOX2B
• Gene Name: paired like homeobox 2b
• Gene Aliases: NBLST2, NBPhox, PMX2B
• Chromosome Location: Chr.4: 41744082 - 41748970 on Build GRCh38
• UniGene ID: Hs.87202
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PHOX2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003924.3	NP_003915.2	3	1399
GenBank mRNA	BC017199.2	-	3	1135	3161284
	D82344.1	-	3	1399

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

neuron migration
regulation of respiratory gaseous exchange by neurological system process
noradrenergic neuron differentiation
noradrenergic neuron development
brainstem development
transcription from RNA polymerase II promoter
negative regulation of cell proliferation
glial cell differentiation
regulation of gene expression
positive regulation of G2/M transition of mitotic cell cycle
cell differentiation in hindbrain
medullary reticular formation development
hindbrain tangential cell migration
skeletal muscle cell differentiation
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
autonomic nervous system development
enteric nervous system development
sympathetic nervous system development
parasympathetic nervous system development
inner ear development
efferent axon development in a lateral line nerve
respiratory system development
retrotrapezoid nucleus neuron differentiation
sympathetic ganglion development
negative regulation of cell cycle arrest
dopaminergic neuron differentiation
cellular response to BMP stimulus
neural crest cell migration involved in autonomic nervous system development

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding