48413

• Gene Symbol: Apoa1
• Gene Name: apolipoprotein A-I
• Gene Aliases: apoA-I
• Chromosome Location: Chr.8: 50525091 - 50526875 on Build Rnor_6.0
• UniGene ID: Rn.10308
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Apoa1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012738.1	NP_036870.1	4	780
GenBank mRNA	BC089820.1	-	3	764	7321674
	FQ209434.1	-	4	781
	FQ209776.1	-	5	736
	FQ209818.1	-	4	786
	FQ209900.1	-	4	781
	FQ209928.1	-	4	785
	FQ209958.1	-	4	785
	FQ210010.1	-	4	785
	FQ210126.1	-	4	782
	FQ210161.1	-	4	808
	FQ210244.1	-	1	442
	FQ210354.1	-	4	785
	FQ210371.1	-	4	782
	FQ210470.1	-	4	781
	FQ210544.1	-	4	783
	FQ210653.1	-	4	783
	FQ210722.1	-	4	785
	FQ210732.1	-	1	422
	FQ210863.1	-	4	785
	FQ210880.1	-	4	781
	FQ210914.1	-	4	781
	FQ211297.1	-	4	783
	FQ211535.1	-	4	788
	FQ211571.1	-	4	781
	FQ218078.1	-	4	781
	FQ218079.1	-	4	785
	FQ218325.1	-	4	785
	FQ218519.1	-	4	781
	FQ218663.1	-	4	781
	FQ218837.1	-	4	787
	FQ219021.1	-	4	785
	FQ219074.1	-	4	781
	FQ219479.1	-	4	873
	FQ219515.1	-	4	785
	FQ219577.1	-	4	781
	FQ219728.1	-	4	780
	FQ220986.1	-	4	782
	FQ224655.1	-	4	781
	FQ229884.1	-	4	820
	M00001.1	-	4	780
	X00558.1	-	3	769

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001373.

Panther Classification:

Molecular Function -

apolipoprotein

Gene Ontology Categories:

Process(es)

regulation of protein phosphorylation
endothelial cell proliferation
negative regulation of cytokine secretion involved in immune response
phospholipid metabolic process
phosphatidylcholine biosynthetic process
cholesterol biosynthetic process
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
response to nutrient
protein localization
cholesterol metabolic process
glucocorticoid metabolic process
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
negative regulation of very-low-density lipoprotein particle remodeling
peripheral nervous system axon regeneration
phospholipid transport
protein oxidation
peptidyl-methionine modification
lipid storage
regulation of intestinal cholesterol absorption
cholesterol transport
adrenal gland development
organ regeneration
axon regeneration
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
negative regulation of heterotypic cell-cell adhesion
very-low-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
positive regulation of Rho protein signal transduction
lipoprotein metabolic process
lipoprotein biosynthetic process
response to drug
cholesterol homeostasis
blood vessel endothelial cell migration
response to estrogen
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
negative regulation of interleukin-1 beta secretion
negative regulation of inflammatory response
protein stabilization
negative chemotaxis
positive regulation of lipoprotein lipase activity
vitamin transport
positive regulation of hydrolase activity
negative regulation of hydrolase activity
positive regulation of transferase activity
positive regulation of stress fiber assembly
phospholipid homeostasis
negative regulation of lipase activity
negative regulation of cell adhesion molecule production
negative regulation of response to cytokine stimulus
triglyceride homeostasis
ERK1 and ERK2 cascade
cholesterol import
positive regulation of substrate adhesion-dependent cell spreading

Function(s)

beta-amyloid binding
lipid transporter activity
phospholipid binding
phospholipid transporter activity
high-density lipoprotein particle binding
lipid binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
apolipoprotein receptor binding
apolipoprotein A-I receptor binding
identical protein binding
chemorepellent activity
lipase inhibitor activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding
lipoprotein particle binding