48502

• Gene Symbol: Il10
• Gene Name: interleukin 10
• Gene Aliases: IL10X
• Chromosome Location: Chr.13: 47739187 - 47743392 on Build Rnor_6.0
• UniGene ID: Rn.9868
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Il10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012854.2	NP_036986.2	2	183
	XM_006249712.2	XP_006249774.1	2	522
	XM_008769426.1	XP_008767648.1	2	522
GenBank mRNA	L02926.1	-	2	183
	X60675.1	-		226

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010548, BC120612, M37897, AK152344, BC137844.

Gene Ontology Categories:

Process(es)

negative regulation of cytokine production
response to molecule of bacterial origin
negative regulation of cytokine secretion involved in immune response
negative regulation of chronic inflammatory response to antigenic stimulus
positive regulation of B cell apoptotic process
inflammatory response
immune response
aging
response to organic substance
regulation of gene expression
response to activity
response to inactivity
negative regulation of myeloid dendritic cell activation
negative regulation of B cell proliferation
response to lipopolysaccharide
negative regulation of interferon-gamma production
negative regulation of interleukin-12 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
receptor biosynthetic process
response to insulin
response to carbon monoxide
response to drug
negative regulation of tumor necrosis factor biosynthetic process
defense response to bacterium
negative regulation of apoptotic process
negative regulation of growth of symbiont in host
negative regulation of nitric oxide biosynthetic process
positive regulation of MHC class II biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
positive regulation of cytokine secretion
negative regulation of inflammatory response
negative regulation of membrane protein ectodomain proteolysis
positive regulation of sequence-specific DNA binding transcription factor activity
response to glucocorticoid
regulation of sensory perception of pain
branching involved in labyrinthine layer morphogenesis
cellular response to lipopolysaccharide
cellular response to estradiol stimulus
regulation of complement-dependent cytotoxicity
negative regulation of endothelial cell apoptotic process

Function(s)

cytokine activity
interleukin-10 receptor binding