4868

• Gene Symbol: CUL3
• Gene Name: cullin 3
• Gene Aliases: CUL-3, PHA2E
• Chromosome Location: Chr.2: 224470150 - 224585397 on Build GRCh38
• UniGene ID: Hs.372286
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CUL3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001257198.1	NP_001244127.1	2, 3	343
	NM_003590.4	NP_003581.1	2, 3	660
	XM_006712800.2	XP_006712863.2	2, 3	333
	XM_011511995.1	XP_011510297.1	2, 3	245
	XM_011511996.2	XP_011510298.1	2, 3	309
GenBank mRNA	AB014517.2	-	2, 3	588
	AF062537.1	-	2, 3	361
	AF064087.1	-	2, 3	353
	AK291151.1	-	2, 3	310
	AK308496.1	-	2, 3	343
	AY337761.1	-	2, 3	806
	BC039598.1	-	2, 3	605	5784147
	BC092409.1	-	2, 3	605	6168545
	BQ688156.1	-		660

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008767226, XM_008767227, BC168969.
This siRNA also targets the following transcripts in Mouse: NM_016716, BC027304, AK129174, AF129738.

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
protein polyubiquitination
trophectodermal cellular morphogenesis
protein monoubiquitination
ER to Golgi vesicle-mediated transport
cell cycle arrest
mitotic metaphase plate congression
integrin-mediated signaling pathway
gastrulation
negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation
positive regulation of cell proliferation
Wnt signaling pathway
cell migration
protein ubiquitination
stem cell division
cell projection organization
positive regulation of cytokinesis
negative regulation of Rho protein signal transduction
embryonic cleavage
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
stress fiber assembly
proteasome-mediated ubiquitin-dependent protein catabolic process
fibroblast apoptotic process
positive regulation of mitotic metaphase/anaphase transition
COPII vesicle coating
liver morphogenesis
negative regulation of canonical Wnt signaling pathway
intrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
protein binding
cyclin binding
POZ domain binding
ubiquitin protein ligase binding
protein homodimerization activity
protein heterodimerization activity
ubiquitin protein ligase activity