48947

Gene Symbol:

Hmgb1 Hmg1l1 Hmgb1-ps2

Gene Name:

high mobility group box 1

high-mobility group (nonhistone chromosomal) protein 1-like 1

high mobility group box 1, pseudogene 2

Gene Aliases:

Ac2-008, Hmg1

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Chromosome Location:

Chr.12: 7090927 - 7092190 on Build Rnor_6.0

Chromosome Location:

Chr.19: 59984234 - 59985494 on Build Rnor_6.0

Chromosome Location:

Chr.17: 30735671 - 30737550 on Build Rnor_6.0

UniGene ID:

Rn.144565

Rn.151172

Rn.196610

Species:

Rat

Species Specific ID (Flybase ID):

-

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siRNA Details

Gene Symbol: Hmgb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012963.2	NP_037095.1		536
GenBank mRNA	AF275734.1	-		568
	BC061779.1	-		524
	BC081839.1	-		536
	BC088402.1	-		612
	M64986.1	-		601
	Y00463.1	-		506

Gene Symbol: Hmg1l1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BC168143.1	-	1	616	9100911

Gene Symbol: Hmgb1-ps2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BC166865.1	-	1	929

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010439, Z11997, AK050659, BC100312, BC006586, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
eye development
positive regulation of protein phosphorylation
positive regulation of mesenchymal cell proliferation
inflammatory response to antigenic stimulus
base-excision repair, DNA ligation
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
chemotaxis
nervous system development
circadian rhythm
negative regulation of DNA replication
positive regulation of cell proliferation
response to heat
response to glucose
positive regulation of cell death
positive regulation of neuron projection development
positive regulation of smooth muscle cell migration
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
lung development
positive regulation of cell migration
neuron projection development
actin cytoskeleton reorganization
DNA geometric change
response to lipopolysaccharide
response to insulin
positive regulation of myeloid cell apoptotic process
V(D)J recombination
response to interferon-gamma
response to drug
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of DNA binding
positive regulation of myeloid cell differentiation
positive regulation of myoblast differentiation
positive regulation of glycogen catabolic process
positive regulation of protein kinase activity
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
regulation of inflammatory response
male-specific defense response to bacterium
induction of positive chemotaxis
response to glucocorticoid
myoblast proliferation
cellular response to interleukin-1

Function(s)

four-way junction DNA binding
open form four-way junction DNA binding
crossed form four-way junction DNA binding
DNA binding
bent DNA binding
chromatin binding
double-stranded DNA binding
single-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
cytokine activity
protein binding
5S rRNA binding
transcription factor binding
heparin binding
DNA binding, bending
calcium-dependent protein kinase regulator activity
protein kinase activator activity
peptide binding
poly(A) RNA binding
protein dimerization activity
RAGE receptor binding
glycolipid binding
repressing transcription factor binding