4910

• Gene Symbol: TNFRSF10B
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Chromosome Location: Chr.8: 23020133 - 23069187 on Build GRCh38
• UniGene ID: Hs.521456
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFRSF10B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003842.4	NP_003833.4	3, 4	654
	NM_147187.2	NP_671716.2	3, 4	654
	NR_027140.1		2, 3	548
	XM_017013944.1	XP_016869433.1	3, 4	442
GenBank mRNA	AB451272.1	-	3, 4	361
	AB451399.1	-	3, 4	361
	AF012535.1	-	3, 4	500
	AF012628.1	-	3, 4	361
	AF016266.1	-	3, 4	478
	AF016268.1	-	3, 4	470
	AF016849.1	-	3, 4	505
	AF018657.1	-	3, 4	361
	AF018658.1	-	3, 4	361
	AF020501.1	-	3, 4	361
	AF022386.1	-	3, 4	361
	AF153687.1	-	3, 4	479
	AF192548.1	-	3, 4	461
	AK291216.1	-	3, 4	481
	AK298602.1	-	2, 3	392
	AL529460.3	-	3, 4	654
	AY358277.1	-	3, 4	500
	BC001281.1	-	3, 4	508	3458466
	CR541898.1	-	3, 4	361
	DA738472.1	-	3, 4	654
	DA889488.1	-	3, 4	498
	FJ200482.1	-	2, 3	255

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding