49114

• Gene Symbol: Parp1
• Gene Name: poly (ADP-ribose) polymerase 1
• Gene Aliases: ARTD1, Adprt, Parp-1
• Chromosome Location: Chr.13: 98857255 - 98889444 on Build Rnor_6.0
• UniGene ID: Rn.11327
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Parp1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013063.2	NP_037195.1	4	616
GenBank mRNA	BC085765.1	-	4	616	7107130
	U94340.1	-	4	584

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_007415, AK088679, AK030889, X14206, AK146677, and others.

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

telomere maintenance
DNA metabolic process
base-excision repair
double-strand break repair
transcription, DNA-templated
protein ADP-ribosylation
transforming growth factor beta receptor signaling pathway
protein autoprocessing
signal transduction involved in regulation of gene expression
cellular response to insulin stimulus
regulation of growth rate
DNA damage response, detection of DNA damage
positive regulation of transcription from RNA polymerase II promoter
positive regulation of SMAD protein import into nucleus
protein poly-ADP-ribosylation
cellular response to superoxide
positive regulation of transcription regulatory region DNA binding

Function(s)

DNA binding
NAD+ ADP-ribosyltransferase activity
transcription factor binding
zinc ion binding
transferase activity, transferring pentosyl groups
enzyme binding
protein kinase binding
identical protein binding
poly(A) RNA binding
protein N-terminus binding
NAD binding
R-SMAD binding