49138

• Gene Symbol: Tnfrsf1a
• Gene Name: tumor necrosis factor receptor superfamily, member 1a
• Gene Aliases: TNFR-1, Tnfr1
• Chromosome Location: Chr.4: 157864916 - 157877634 on Build Rnor_6.0
• UniGene ID: Rn.11119
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tnfrsf1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013091.1	NP_037223.1	2, 3	438
GenBank mRNA	AF329976.1	-	2, 3	437
	AF329977.1	-	2, 3	437
	AF329978.1	-	2, 3	437
	AF329979.1	-	2, 3	437
	AF329980.1	-	2, 3	437
	AF329981.1	-	2, 3	437
	BC086413.1	-	2, 3	458	7110094
	M63122.1	-	2, 3	438

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_011609, X57796, AY541590, M60468, AK159989, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

response to hypoxia
prostaglandin metabolic process
defense response
inflammatory response
cell surface receptor signaling pathway
intrinsic apoptotic signaling pathway in response to DNA damage
response to wounding
positive regulation of gene expression
negative regulation of gene expression
programmed cell death
cytokine-mediated signaling pathway
response to lipopolysaccharide
negative regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
tetrapyrrole metabolic process
positive regulation of protein import into nucleus, translocation
tumor necrosis factor-mediated signaling pathway
positive regulation of tyrosine phosphorylation of Stat1 protein
defense response to bacterium
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
response to alkaloid
positive regulation of neuron apoptotic process
response to ethanol
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
negative regulation of inflammatory response
positive regulation of inflammatory response
protein heterooligomerization
cellular response to mechanical stimulus
cellular response to estradiol stimulus

Function(s)

protease binding
tumor necrosis factor-activated receptor activity
protein binding
protein complex binding
tumor necrosis factor binding