49275

• Gene Symbol: Cntf
• Gene Name: ciliary neurotrophic factor
• Gene Aliases: -
• Chromosome Location: Chr.1: 229599009 - 229601032 on Build Rnor_6.0
• UniGene ID: Rn.6067
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Cntf
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013166.1	NP_037298.1	1	159
GenBank mRNA	FQ216326.1	-	1	122
	X17457.1	-	1	159

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_000614, BC074963, DB241497, AB057443, BC074964, and others.
This siRNA also targets the following transcripts in Mouse: NM_170786, BC027539, W08735, U05342, AK041204.

Gene Ontology Categories:

Process(es)

JAK-STAT cascade
nervous system development
positive regulation of cell proliferation
response to light intensity
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of cell growth
growth
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
positive regulation of JAK-STAT cascade
negative regulation of photoreceptor cell differentiation
regulation of retinal cell programmed cell death
positive regulation of hormone secretion
astrocyte activation
muscle organ morphogenesis
neuron development
positive regulation of axon regeneration
protein heterooligomerization
response to electrical stimulus
regulation of resting membrane potential
membrane hyperpolarization
ciliary neurotrophic factor-mediated signaling pathway
negative regulation of neuron death

Function(s)

cytokine activity
ciliary neurotrophic factor receptor binding
interleukin-6 receptor binding
growth factor activity