49529

• Gene Symbol: Itgb1
• Gene Name: integrin, beta 1
• Gene Aliases: -
• Chromosome Location: Chr.19: 61677512 - 61725537 on Build Rnor_6.0
• UniGene ID: Rn.25733
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Itgb1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017022.2	NP_058718.2	10, 11	1447
	XM_006255824.1	XP_006255886.1	10, 11	1477
GenBank mRNA	BC131845.1	-	10, 11	1447	8366766
	U12309.1	-	10, 11	1321

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_002211, NM_133376, NM_033668, BC020057, BX537407, and others.
This siRNA also targets the following transcripts in Mouse: NM_010578, BC050906, X15202, AK167682, AK141253, and others.

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
in utero embryonic development
cell fate specification
tissue homeostasis
cell migration involved in sprouting angiogenesis
cellular calcium ion homeostasis
cell adhesion
leukocyte cell-cell adhesion
cell-matrix adhesion
calcium-independent cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of cell proliferation
negative regulation of cell proliferation
germ cell migration
visual learning
regulation of collagen catabolic process
positive regulation of cell-substrate adhesion
positive regulation of neuron projection development
response to activity
cell migration
formation of radial glial scaffolds
positive regulation of cell migration
neuron projection development
negative regulation of cell projection organization
cell-substrate adhesion
response to nutrient levels
protein transport within lipid bilayer
cell-cell adhesion mediated by integrin
heterotypic cell-cell adhesion
response to gonadotropin
negative regulation of Rho protein signal transduction
response to drug
positive regulation of apoptotic process
stress fiber assembly
positive regulation of MAPK cascade
sarcomere organization
negative regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of endocytosis
mesodermal cell differentiation
axon extension
cardiac muscle tissue development
dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
leukocyte tethering or rolling
regulation of cell cycle
cardiac muscle cell differentiation
maternal process involved in female pregnancy
bicellular tight junction assembly
cellular response to mechanical stimulus
cellular response to vitamin D
cellular response to ionizing radiation
response to transforming growth factor beta
positive regulation of establishment of protein localization to plasma membrane
negative regulation of anoikis

Function(s)

glycoprotein binding
fibronectin binding
protease binding
actin binding
receptor activity
receptor binding
integrin binding
protein binding
collagen binding
kinase binding
protein kinase binding
protein domain specific binding
protein complex binding
peptide binding
laminin binding
metal ion binding
protein heterodimerization activity
cell adhesion molecule binding
alpha-actinin binding
collagen binding involved in cell-matrix adhesion