49640

• Gene Symbol: Ppm1a
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent, 1A
• Gene Aliases: Pp2c1
• Chromosome Location: Chr.6: 94433661 - 94490408 on Build Rnor_6.0
• UniGene ID: Rn.37403
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ppm1a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017038.1	NP_058734.1	2	293
	XM_006240193.2	XP_006240255.1	2	3596
	XM_006240194.2	XP_006240256.1	2	550
	XM_006240195.2	XP_006240257.1	2	314
GenBank mRNA	J04503.1	-	2	293

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_021003, NM_177952, NM_177951, BC063243, AB451371, and others.
This siRNA also targets the following transcripts in Mouse: NM_008910, BC008595, AF369981, AK191727, AF259673, and others.

Gene Ontology Categories:

Process(es)

protein dephosphorylation
N-terminal protein myristoylation
negative regulation of SMAD protein complex assembly
Wnt signaling pathway
dephosphorylation
positive regulation of Wnt signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
peptidyl-threonine dephosphorylation
negative regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription, DNA-templated
positive regulation of protein export from nucleus
cellular response to transforming growth factor beta stimulus

Function(s)

magnesium ion binding
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
signal transducer activity
protein binding
protein C-terminus binding
manganese ion binding
calmodulin-dependent protein phosphatase activity
R-SMAD binding