49945

• Gene Symbol: Pkn1
• Gene Name: protein kinase N1
• Gene Aliases: PAK-1, Prkcl1
• Chromosome Location: Chr.19: 24803524 - 24831500 on Build Rnor_6.0
• UniGene ID: Rn.49880
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pkn1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_017175.2	NP_058871.2	5	839
	XM_006255245.2	XP_006255307.1	5	1879
GenBank mRNA	BC061836.1	-	5	740	5599989
	D26180.1	-	5	790
	FQ222217.1	-	5	839
	L35634.1	-	5	682

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001199593, NM_177262, AK149649, AK134792, AK171297, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

B cell homeostasis
B cell apoptotic process
negative regulation of protein phosphorylation
regulation of germinal center formation
regulation of immunoglobulin production
renal system process
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
signal transduction
epithelial cell migration
negative regulation of B cell proliferation
histone H3-T11 phosphorylation
spleen development
regulation of cell motility

Function(s)

chromatin binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein kinase C binding
ATP binding
GTP-Rho binding
ligand-dependent nuclear receptor transcription coactivator activity
histone kinase activity (H3-T11 specific)
histone binding
histone deacetylase binding
Rac GTPase binding
androgen receptor binding