5003

• Gene Symbol: TNFRSF10B
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Chromosome Location: Chr.8: 23020133 - 23069187 on Build GRCh38
• UniGene ID: Hs.521456
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TNFRSF10B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003842.4	NP_003833.4	9	4087
	NM_147187.2	NP_671716.2	10	4000
	NR_027140.1		9	3894
	XM_017013944.1	XP_016869433.1	9	3875
GenBank mRNA	AF016266.1	-	9	3910
	BX537617.1	-	4	3192
	BX538104.1	-	9	3917
	BX538179.1	-	4	3192

More Information

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding