501051

• Gene Symbol: Gli2
• Gene Name: GLI-Kruppel family member GLI2
• Gene Aliases: AW546128
• Chromosome Location: Chr.1: 118834061 - 119053619 on Build GRCm38
• UniGene ID: Mm.273292
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gli2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001081125.1	NP_001074594.1	4	635
GenBank mRNA	AM262743.1	-	3	249
	AM262744.1	-	5	466
	BC082604.1	-	4	576	30672479
	BC085190.1	-	4	551	30694633
	X99104.1	-	4	395

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107169, XM_008769455.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
osteoblast differentiation
in utero embryonic development
kidney development
morphogenesis of an epithelium
chondrocyte differentiation
osteoblast development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
smoothened signaling pathway
pattern specification process
axon guidance
ventral midline development
hindgut morphogenesis
heart development
cell proliferation
positive regulation of cell proliferation
regulation of smoothened signaling pathway
epidermal cell differentiation
dorsal/ventral pattern formation
proximal/distal pattern formation
floor plate formation
spinal cord dorsal/ventral patterning
ventral spinal cord development
spinal cord motor neuron differentiation
cerebellar cortex morphogenesis
smoothened signaling pathway involved in ventral spinal cord interneuron specification
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
dorsal/ventral neural tube patterning
neural tube development
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
spinal cord ventral commissure morphogenesis
pituitary gland development
cell differentiation
lung development
mammary gland development
hindbrain development
negative regulation of chondrocyte differentiation
tube development
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of neuron differentiation
positive regulation of DNA replication
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract development
developmental growth
anatomical structure formation involved in morphogenesis
neuron development
branching morphogenesis of an epithelial tube
anatomical structure development
notochord regression
head development
prostatic bud formation
mammary gland duct morphogenesis
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
cellular response to organic cyclic compound
cochlea morphogenesis
cellular response to virus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
nucleic acid binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding