501738

• Gene Symbol: Agap2
• Gene Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
• Gene Aliases: AGAP-2, Centg1, PIKE, cnt-g1, mKIAA0167
• Chromosome Location: Chr.10: 127075258 - 127093173 on Build GRCm38
• UniGene ID: Mm.336761
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Agap2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001033263.5	NP_001028435.1	19	5040
	NM_001301014.1	NP_001287943.1	18	4980
GenBank mRNA	AK049954.1	-	1	62
	AK147446.1	-	19	5041
	AK220325.1	-	18	3854

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001122772, NM_014770, D79989, AF384128.
This siRNA also targets the following transcripts in Rat: NM_023026.

Gene Ontology Categories:

Process(es)

small GTPase mediated signal transduction
positive regulation of phosphatidylinositol 3-kinase signaling
endosomal transport
actin cytoskeleton organization
positive regulation of mammary gland epithelial cell proliferation
negative regulation of protein catabolic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
regulation of phosphatidylinositol 3-kinase activity
positive regulation of protein kinase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
mammary gland alveolus development
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

nucleotide binding
GTPase activity
GTPase activator activity
protein binding
ATP binding
GTP binding
protein kinase binding
protein kinase activator activity
phosphatidylinositol 3-kinase regulator activity
metal ion binding