503932

• Gene Symbol: Nlrp12
• Gene Name: NLR family, pyrin domain containing 12
• Gene Aliases: Nalp12, PYPAF7
• Chromosome Location: Chr.7: 3218643 - 3250159 on Build GRCm38
• UniGene ID: Mm.277152
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nlrp12
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001033431.1	NP_001028603.1	3	1343
GenBank mRNA	AK158158.1	-	3	1344
	AY364010.1	-	2	1079
	BC116252.1	-	3	1216	40093617
	BC116253.1	-	3	1216	40093618

More Information

Gene Ontology Categories:

Process(es)

release of cytoplasmic sequestered NF-kappaB
negative regulation of signal transduction
negative regulation of protein autophosphorylation
negative regulation of NF-kappaB transcription factor activity
dendritic cell migration
regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MHC class I biosynthetic process
negative regulation of interleukin-6 biosynthetic process
negative regulation of Toll signaling pathway
negative regulation of cytokine secretion
negative regulation of interleukin-1 secretion
negative regulation of inflammatory response
negative regulation of ERK1 and ERK2 cascade
cellular response to cytokine stimulus
negative regulation of NIK/NF-kappaB signaling

Function(s)

nucleotide binding
protein binding
ATP binding