50517

• Gene Symbol: Il18
• Gene Name: interleukin 18
• Gene Aliases: IL-18
• Chromosome Location: Chr.8: 55009666 - 55016286 on Build Rnor_6.0
• UniGene ID: Rn.11118
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Il18
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019165.1	NP_062038.1	4	317
GenBank mRNA	AJ222813.1	-	4	317
	AY077842.1	-		545
	AY258448.1	-	4	317
	U77776.1	-	4	317
	U77777.1	-	4	317

More Information

Panther Classification:

Molecular Function -

cytokine, interleukin superfamily, intercellular signal molecule

Gene Ontology Categories:

Process(es)

MAPK cascade
angiogenesis
osteoblast differentiation
response to hypoxia
inflammatory response
learning or memory
response to radiation
response to cold
positive regulation of gene expression
positive regulation of smooth muscle cell migration
natural killer cell activation
regulation of cell adhesion
lung development
sleep
lipopolysaccharide-mediated signaling pathway
positive regulation of chemokine production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-17 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of natural killer cell proliferation
positive regulation of superoxide anion generation
positive regulation of collagen biosynthetic process
negative regulation of neutrophil apoptotic process
T-helper 1 type immune response
interferon-gamma biosynthetic process
positive regulation of activated T cell proliferation
positive regulation of NF-kappaB import into nucleus
positive regulation of apoptotic process
positive regulation of vascular permeability
response to peptide hormone
positive regulation of neuron apoptotic process
regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of myoblast differentiation
digestive tract morphogenesis
positive regulation of smooth muscle cell proliferation
negative regulation of peptidyl-tyrosine phosphorylation
detection of mechanical stimulus involved in sensory perception of pain
positive regulation of NK T cell proliferation
response to hyperoxia
cellular response to hydrogen peroxide
cellular response to lipopolysaccharide
cellular response to mechanical stimulus
cellular response to cAMP
cellular response to interferon-gamma
cellular response to tumor necrosis factor
cellular response to parathyroid hormone stimulus
cellular response to peptide hormone stimulus
cellular response to organic cyclic compound
positive regulation of male germ cell proliferation
positive regulation of blood vessel remodeling

Function(s)

cytokine activity
protein binding