50682

• Gene Symbol: P2rx7
• Gene Name: purinergic receptor P2X, ligand-gated ion channel, 7
• Gene Aliases: -
• Chromosome Location: Chr.12: 39353613 - 39396042 on Build Rnor_6.0
• UniGene ID: Rn.10510
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: P2rx7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_019256.1	NP_062129.1	2	339
	XM_008769223.1	XP_008767445.1	2	513
GenBank mRNA	FJ436445.1	-	2	377
	X95882.1	-	2	339

More Information

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

activation of MAPK activity
cell morphogenesis
phagolysosome assembly
positive regulation of T cell mediated cytotoxicity
positive regulation of protein phosphorylation
regulation of sodium ion transport
protein phosphorylation
membrane protein ectodomain proteolysis
phospholipid transfer to membrane
cation transport
calcium ion transport
cell volume homeostasis
membrane budding
inflammatory response
mitochondrion organization
plasma membrane organization
cell surface receptor signaling pathway
response to mechanical stimulus
response to bacterium
response to organic substance
response to zinc ion
gene expression
positive regulation of calcium ion transport into cytosol
programmed cell death
positive regulation of glutamate secretion
positive regulation of gamma-aminobutyric acid secretion
response to organic cyclic compound
organic cation transport
synaptic vesicle exocytosis
protein processing
neuronal action potential
sensory perception of pain
cytolysis
positive regulation of bone mineralization
cellular response to extracellular stimulus
bleb assembly
positive regulation of prostaglandin secretion
response to lipopolysaccharide
positive regulation of interleukin-1 beta production
positive regulation of interleukin-6 production
collagen metabolic process
response to ATP
response to fluid shear stress
purinergic nucleotide receptor signaling pathway
T cell proliferation
response to drug
T cell homeostasis
positive regulation of apoptotic process
positive regulation of catalytic activity
NAD transport
negative regulation of MAPK cascade
positive regulation of MAPK cascade
multicellular organismal protein catabolic process
phospholipid translocation
positive regulation of ossification
negative regulation of bone resorption
positive regulation of cytolysis
ceramide biosynthetic process
pore complex assembly
skeletal system morphogenesis
homeostasis of number of cells within a tissue
positive regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of interleukin-1 alpha secretion
positive regulation of interleukin-1 beta secretion
defense response to Gram-positive bacterium
release of sequestered calcium ion into cytosol
protein oligomerization
positive regulation of cytoskeleton organization
response to calcium ion
response to electrical stimulus
membrane depolarization
positive regulation of mitochondrial depolarization
positive regulation of lymphocyte apoptotic process
cellular response to organic cyclic compound
reactive oxygen species metabolic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
cation transmembrane transport

Function(s)

magnesium ion binding
lipopolysaccharide binding
purinergic nucleotide receptor activity
receptor activity
extracellular ATP-gated cation channel activity
receptor binding
copper ion binding
protein binding
ATP binding
zinc ion binding
channel activity
protein serine/threonine kinase activator activity
scaffold protein binding