5081

• Gene Symbol: DUSP1
• Gene Name: dual specificity phosphatase 1
• Gene Aliases: CL100, HVH1, MKP-1, MKP1, PTPN10
• Chromosome Location: Chr.5: 172768090 - 172771200 on Build GRCh38
• UniGene ID: Hs.171695
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DUSP1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004417.3	NP_004408.1	3	901
GenBank mRNA	AK298047.1	-	4	835
	AK298658.1	-	4	701
	AK299391.1	-	4	905
	AK300487.1	-	4	815
	AK304475.1	-	4	693
	AK316321.1	-	4	644
	BC022463.1	-	3	896	4794895
	X68277.1	-	3	886

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053769, U02553, S81478, X84004.
This siRNA also targets the following transcripts in Mouse: NM_013642, AK145903, AK152905, AK159658, AK167602, and others.

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

inactivation of MAPK activity
endoderm formation
response to oxidative stress
response to light stimulus
response to estradiol
response to retinoic acid
cellular response to hormone stimulus
response to testosterone
peptidyl-tyrosine dephosphorylation
intracellular signal transduction
peptidyl-threonine dephosphorylation
response to hydrogen peroxide
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
response to glucocorticoid
negative regulation of meiotic cell cycle
response to cAMP
response to calcium ion
negative regulation of ERK1 and ERK2 cascade
mitotic cell cycle arrest
regulation of mitotic cell cycle spindle assembly checkpoint
negative regulation of DNA biosynthetic process

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding
protein tyrosine/threonine phosphatase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
growth factor binding