51009

• Gene Symbol: Pitx2
• Gene Name: paired-like homeodomain 2
• Gene Aliases: Pitx-2, Pitx2c, Ptx2
• Chromosome Location: Chr.2: 233602732 - 233621055 on Build Rnor_6.0
• UniGene ID: Rn.17591
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pitx2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042505.1	NP_001035970.1	2	643
	NM_019334.2	NP_062207.1	3	344
GenBank mRNA	AF039832.1	-	3	344
	AJ222971.1	-	2	651
	AJ222972.1	-	3	397
	EF519321.1	-	2	133

More Information

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
patterning of blood vessels
vasculogenesis
in utero embryonic development
neuron migration
extraocular skeletal muscle development
atrioventricular valve development
cardiac neural crest cell migration involved in outflow tract morphogenesis
pulmonary myocardium development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
determination of left/right symmetry
brain development
heart development
skeletal muscle tissue development
myoblast fusion
male gonad development
female gonad development
anatomical structure morphogenesis
response to hormone
organ morphogenesis
Wnt signaling pathway
subthalamic nucleus development
hypothalamus cell migration
pituitary gland development
neuron differentiation
lung development
regulation of cell migration
embryonic camera-type eye development
response to vitamin A
embryonic hindlimb morphogenesis
vascular smooth muscle cell differentiation
deltoid tuberosity development
regulation of cell proliferation
odontogenesis of dentin-containing tooth
odontogenesis
camera-type eye development
positive regulation of DNA binding
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
spleen development
embryonic digestive tract morphogenesis
cardiac muscle tissue development
cardiac muscle cell differentiation
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle cell development
digestive system development
ventricular septum morphogenesis
left lung morphogenesis
pulmonary vein morphogenesis
superior vena cava morphogenesis
endodermal digestive tract morphogenesis
iris morphogenesis
cell proliferation involved in outflow tract morphogenesis
left/right axis specification
positive regulation of myoblast proliferation

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
transcriptional repressor activity, RNA polymerase II transcription factor binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
chromatin DNA binding
identical protein binding
protein homodimerization activity
sequence-specific DNA binding
phosphoprotein binding