51258

• Gene Symbol: Nr1h4
• Gene Name: nuclear receptor subfamily 1, group H, member 4
• Gene Aliases: Fxr
• Chromosome Location: Chr.7: 30003429 - 30162095 on Build Rnor_6.0
• UniGene ID: Rn.42943
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nr1h4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021745.1	NP_068513.1	3, 4	615
	XM_008765260.1	XP_008763482.1	2, 3	973
	XM_008765261.1	XP_008763483.1	2, 3	972
	XM_008765262.1	XP_008763484.1	3, 4	654
GenBank mRNA	BC083815.1	-	2, 3	493	7110420
	U18374.1	-	3, 4	615

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009108, NM_001163700, NM_001163504, U09416, U09418, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of carbohydrate metabolic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
bile acid metabolic process
response to glucose
intracellular receptor signaling pathway
response to lipopolysaccharide
regulation of urea metabolic process
intracellular bile acid receptor signaling pathway
steroid hormone mediated signaling pathway
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
negative regulation of bile acid biosynthetic process
cellular response to organonitrogen compound
cellular response to bile acid
positive regulation of glutamate metabolic process
positive regulation of ammonia assimilation cycle

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
steroid hormone receptor activity
receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
thyroid hormone receptor activity
zinc ion binding
bile acid binding
bile acid receptor activity
peptide binding
sequence-specific DNA binding
retinoid X receptor binding
chenodeoxycholic acid binding