51738

• Gene Symbol: Casp8
• Gene Name: caspase 8
• Gene Aliases: -
• Chromosome Location: Chr.9: 65614142 - 65662624 on Build Rnor_6.0
• UniGene ID: Rn.54474
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Casp8
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022277.1	NP_071613.1	2	430
	XM_006245014.2	XP_006245076.1	2	412
	XM_006245015.2	XP_006245077.1	2	553
	XM_008767135.1	XP_008765357.1	2	412
GenBank mRNA	AF279308.1	-	2	430
	AF288372.1	-	2	165
	FQ226407.1	-	2	444

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

angiogenesis
neural tube formation
proteolysis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
heart development
extrinsic apoptotic signaling pathway via death domain receptors
response to cold
macrophage differentiation
response to cobalt ion
response to estradiol
response to lipopolysaccharide
response to tumor necrosis factor
TRAIL-activated apoptotic signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to ethanol
positive regulation of macrophage differentiation
positive regulation of proteolysis
response to antibiotic
protein heterooligomerization
proteolysis involved in cellular protein catabolic process
negative regulation of necroptotic process
regulation of thymocyte apoptotic process
cellular response to mechanical stimulus
cellular response to organic cyclic compound
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
execution phase of apoptosis
activation of cysteine-type endopeptidase activity
hepatocyte apoptotic process
regulation of apoptotic signaling pathway
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

endopeptidase activity
cysteine-type endopeptidase activity
death receptor binding
tumor necrosis factor receptor binding
protein binding
peptidase activity
ubiquitin protein ligase binding
protein complex binding
death effector domain binding
protein heterodimerization activity
scaffold protein binding
cysteine-type endopeptidase activity involved in apoptotic process
cysteine-type endopeptidase activity involved in apoptotic signaling pathway