51795

• Gene Symbol: Prkcz
• Gene Name: protein kinase C, zeta
• Gene Aliases: 14-3-3-zetaisoform, Pkcz, r14-3-3
• Chromosome Location: Chr.5: 172658071 - 172769492 on Build Rnor_6.0
• UniGene ID: Rn.1109
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Prkcz
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022507.1	NP_071952.1	2	281
	XM_008764337.1	XP_008762559.1	2	182
GenBank mRNA	J04532.1	-	2	281

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008860, CK339309, BY073558, M94632, AK165750, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

microtubule cytoskeleton organization
positive regulation of cell-matrix adhesion
protein phosphorylation
inflammatory response
signal transduction
cell surface receptor signaling pathway
long-term memory
positive regulation of cell proliferation
insulin receptor signaling pathway
cell migration
peptidyl-serine phosphorylation
establishment of cell polarity
negative regulation of protein complex assembly
actin cytoskeleton reorganization
activation of phospholipase D activity
activation of protein kinase B activity
positive regulation of interleukin-4 production
cellular response to insulin stimulus
cellular protein localization
intracellular signal transduction
negative regulation of apoptotic process
positive regulation of T-helper 2 cell differentiation
positive regulation of glucose import
negative regulation of insulin receptor signaling pathway
positive regulation of insulin receptor signaling pathway
vesicle transport along microtubule
negative regulation of peptidyl-tyrosine phosphorylation
positive regulation of synaptic transmission
positive regulation of NF-kappaB transcription factor activity
positive regulation of protein transport
protein heterooligomerization
negative regulation of hydrolase activity
membrane depolarization
membrane hyperpolarization
long-term synaptic potentiation
positive regulation of ERK1 and ERK2 cascade
protein kinase C signaling
protein localization to plasma membrane
neuron projection extension
positive regulation of excitatory postsynaptic potential
positive regulation of T-helper 2 cell cytokine production
positive regulation of interleukin-5 secretion
positive regulation of interleukin-13 secretion
positive regulation of interleukin-10 secretion

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
protein binding
ATP binding
potassium channel regulator activity
protein kinase binding
protein domain specific binding
phospholipase binding
metal ion binding
14-3-3 protein binding