51959

Gene Symbol:

Mthfd1 LOC680432

Gene Name:

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

similar to methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

Gene Aliases:

-

-

Chromosome Location:

Chr.6: 99282850 - 99350367 on Build Rnor_6.0

Chromosome Location:

Chr.3: 121490785 - 121493932 on Build Rnor_6.0

UniGene ID:

Rn.1114

-

Species:

Rat

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: Mthfd1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022508.1	NP_071953.1	7, 8	929
	XM_006240249.2	XP_006240311.1	7, 8	1068
GenBank mRNA	BC089800.1	-	7, 8	643	7323085
	J05519.1	-	7, 8	929

Gene Symbol: LOC680432
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_008762232.1	XP_008760454.1	1	656

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_138745, AK208410, BC013563, AK133848, AK042019, and others.

Gene Ontology Categories:

Process(es)

histidine biosynthetic process
purine nucleotide biosynthetic process
one-carbon metabolic process
methionine biosynthetic process
nucleotide metabolic process
folic acid-containing compound biosynthetic process
tetrahydrofolate interconversion
tetrahydrofolate metabolic process
oxidation-reduction process

Function(s)

formate-tetrahydrofolate ligase activity
methenyltetrahydrofolate cyclohydrolase activity
methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
methylenetetrahydrofolate dehydrogenase (NADP+) activity
ATP binding
hydrolase activity