52040

• Gene Symbol: Wnt5a
• Gene Name: wingless-type MMTV integration site family, member 5A
• Gene Aliases: -
• Chromosome Location: Chr.16: 4469451 - 4488707 on Build Rnor_6.0
• UniGene ID: Rn.48749
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Wnt5a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_022631.1	NP_072153.1	3	477
	XM_006252664.2	XP_006252726.1	3	344
	XM_006252665.2	XP_006252727.1	3	306
	XM_008771007.1	XP_008769229.1	3	1182
GenBank mRNA	AB244721.1	-	2	240
	AF188333.1	-	3	477
	AY819646.1	-	2	240

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001256224, NM_009524, AK036824, AK031597, AK032977, and others.

Panther Classification:

Molecular Function -

intercellular signal molecule

Gene Ontology Categories:

Process(es)

activation of MAPK activity
ameboidal-type cell migration
establishment of planar polarity
somitogenesis
positive regulation of cytokine production
epithelial to mesenchymal transition
neural tube closure
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
heart looping
morphogenesis of an epithelium
positive regulation of mesenchymal cell proliferation
positive regulation of cytokine secretion involved in immune response
type B pancreatic cell development
pericardium morphogenesis
axis elongation
protein phosphorylation
Wnt signaling pathway, calcium modulating pathway
JNK cascade
activation of JUN kinase activity
determination of left/right symmetry
axon guidance
hindgut morphogenesis
midgut development
positive regulation of cell proliferation
male gonad development
anterior/posterior axis specification, embryo
anterior/posterior pattern specification
response to organic substance
positive regulation of endothelial cell migration
positive regulation of peptidyl-threonine phosphorylation
positive regulation of T cell chemotaxis
positive regulation of neuron projection development
response to organic cyclic compound
Wnt signaling pathway
cell migration
olfactory bulb interneuron development
neural tube development
positive regulation of cell-cell adhesion
cell differentiation
neuron differentiation
keratinocyte differentiation
lung development
embryonic limb morphogenesis
negative regulation of BMP signaling pathway
positive regulation of cGMP metabolic process
prostate gland development
activation of protein kinase B activity
response to estradiol
positive regulation of interferon-gamma production
positive regulation of interleukin-6 production
regulation of protein localization
positive regulation of peptidyl-serine phosphorylation
response to testosterone
cellular protein localization
limb morphogenesis
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
non-canonical Wnt signaling pathway via JNK cascade
negative regulation of fibroblast growth factor receptor signaling pathway
wound healing
inner ear morphogenesis
embryonic digit morphogenesis
positive regulation of macrophage activation
negative regulation of apoptotic process
positive regulation of JUN kinase activity
estrous cycle
positive regulation of chemokine biosynthetic process
cell fate commitment
negative regulation of fat cell differentiation
positive regulation of protein catabolic process
positive regulation of angiogenesis
positive regulation of ossification
positive regulation of endocytosis
positive regulation of meiotic nuclear division
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
development of primary male sexual characteristics
positive regulation of fibroblast proliferation
lung alveolus development
digestive tract morphogenesis
embryonic skeletal system development
genitalia development
neuron projection morphogenesis
negative regulation of axon extension involved in axon guidance
hypophysis morphogenesis
positive regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
positive regulation of interleukin-1 beta secretion
positive regulation of inflammatory response
negative chemotaxis
positive regulation of NF-kappaB transcription factor activity
cartilage development
response to glucocorticoid
negative regulation of synapse assembly
response to hyperoxia
palate development
convergent extension
convergent extension involved in organogenesis
uterus development
cervix development
vagina development
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
urinary bladder development
face development
positive regulation of type I interferon-mediated signaling pathway
lateral sprouting involved in mammary gland duct morphogenesis
tube closure
mesenchymal-epithelial cell signaling
negative regulation of prostatic bud formation
mammary gland branching involved in thelarche
epithelial cell proliferation involved in mammary gland duct elongation
positive regulation of response to cytokine stimulus
regulation of branching involved in mammary gland duct morphogenesis
positive regulation of macrophage cytokine production
positive regulation of cartilage development
planar cell polarity pathway involved in outflow tract morphogenesis
planar cell polarity pathway involved in ventricular septum morphogenesis
planar cell polarity pathway involved in cardiac right atrium morphogenesis
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
planar cell polarity pathway involved in pericardium morphogenesis
positive regulation of thymocyte apoptotic process
cellular response to molecule of bacterial origin
cellular response to lipopolysaccharide
cellular response to calcium ion
cellular response to interferon-gamma
hematopoietic stem cell proliferation
dopaminergic neuron differentiation
cellular response to transforming growth factor beta stimulus
negative regulation of mesenchymal cell proliferation
primitive streak formation
positive regulation of protein kinase C signaling
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
positive regulation of cell-cell adhesion mediated by cadherin
positive regulation of interleukin-8 secretion

Function(s)

molecular_function
transcription factor activity, sequence-specific DNA binding
receptor binding
frizzled binding
frizzled-2 binding
receptor tyrosine kinase-like orphan receptor binding
cytokine activity
protein domain specific binding
transcription regulatory region DNA binding