52681

• Gene Symbol: Apex1
• Gene Name: APEX nuclease (multifunctional DNA repair enzyme) 1
• Gene Aliases: APE, Apex, REF-1
• Chromosome Location: Chr.15: 27849943 - 27852083 on Build Rnor_6.0
• UniGene ID: Rn.5949
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Apex1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_024148.1	NP_077062.1	3, 4	350
	XM_006251913.1	XP_006251975.1	3, 4	391
GenBank mRNA	AF309114.1	-	2, 3	266
	AF311054.1	-	2, 3	228
	BC078816.1	-	3, 4	358	7127205
	D44495.1	-	3, 4	350
	FQ220521.1	-	3, 4	352
	L27076.1	-	3, 4	334

More Information

Gene Ontology Categories:

Process(es)

DNA catabolic process, endonucleolytic
DNA catabolic process, exonucleolytic
DNA repair
base-excision repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
aging
response to organonitrogen compound
negative regulation of smooth muscle cell migration
response to drug
regulation of mRNA stability
cell redox homeostasis
positive regulation of DNA repair
oxidation-reduction process
cellular response to hydrogen peroxide
cellular response to cAMP
cellular response to peptide hormone stimulus
cellular response to organonitrogen compound
DNA demethylation
nucleic acid phosphodiester bond hydrolysis
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

DNA binding
damaged DNA binding
transcription coactivator activity
DNA-(apurinic or apyrimidinic site) lyase activity
endonuclease activity
endoribonuclease activity
protein binding
phosphoric diester hydrolase activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
3'-5' exonuclease activity
oxidoreductase activity
site-specific endodeoxyribonuclease activity, specific for altered base
chromatin DNA binding
protein complex binding
poly(A) RNA binding
metal ion binding
NF-kappaB binding