52825

• Gene Symbol: Atf4
• Gene Name: activating transcription factor 4
• Gene Aliases: -
• Chromosome Location: Chr.7: 121480723 - 121482781 on Build Rnor_6.0
• UniGene ID: Rn.2423
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Atf4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_024403.2	NP_077379.1	2	401
GenBank mRNA	AF252627.1	-	1	167
	BC158588.1	-	2	374	9098368
	FQ210065.1	-	2	401
	FQ213021.1	-	2	401
	FQ214151.1	-	2	400
	FQ214217.1	-	2	402
	FQ214457.1	-	2	400
	FQ215912.1	-	2	399
	FQ216049.1	-	2	400
	FQ219043.1	-	2	401
	FQ221881.1	-	2	401
	FQ230257.1	-	1	29
	FQ232693.1	-	2	407

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001675, NM_182810, BC073990, M86842, BC044895, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

gluconeogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
gamma-aminobutyric acid signaling pathway
positive regulation of vascular endothelial growth factor production
circadian regulation of gene expression
response to endoplasmic reticulum stress
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
cellular response to glucose starvation
negative regulation of potassium ion transport
positive regulation of neuron apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase I promoter
positive regulation of transcription from RNA polymerase II promoter
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
negative regulation of oxidative stress-induced neuron death
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein C-terminus binding
transcription factor binding
leucine zipper domain binding
sequence-specific DNA binding
transcription regulatory region DNA binding