52879

• Gene Symbol: Gch1
• Gene Name: GTP cyclohydrolase 1
• Gene Aliases: Gch
• Chromosome Location: Chr.15: 23935011 - 23968971 on Build Rnor_6.0
• UniGene ID: Rn.28195
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gch1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_024356.1	NP_077332.1	1	294
GenBank mRNA	FQ220953.1	-	1	281
	M58364.1	-	1	294

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_001024070, NM_001024071, NM_000161, NM_001024024, S44049, and others.

Panther Classification:

Molecular Function -

hydrolase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

protein complex assembly
tetrahydrobiopterin biosynthetic process
metabolic process
regulation of blood pressure
regulation of lung blood pressure
response to lipopolysaccharide
response to interferon-gamma
response to tumor necrosis factor
7,8-dihydroneopterin 3'-triphosphate biosynthetic process
vasodilation
dopamine biosynthetic process
pteridine-containing compound biosynthetic process
negative regulation of blood pressure
tetrahydrofolate biosynthetic process
response to pain
neuromuscular process controlling posture
positive regulation of nitric-oxide synthase activity
dihydrobiopterin metabolic process
protein homooligomerization
protein heterooligomerization

Function(s)

GTP cyclohydrolase I activity
calcium ion binding
protein binding
GTP binding
zinc ion binding
GTP-dependent protein binding
protein homodimerization activity
coenzyme binding