5323

• Gene Symbol: HAND1
• Gene Name: heart and neural crest derivatives expressed 1
• Gene Aliases: Hxt, Thing1, bHLHa27, eHand
• Chromosome Location: Chr.5: 154474972 - 154478264 on Build GRCh38
• UniGene ID: Hs.152531
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HAND1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004821.2	NP_004812.1	1	720
	XM_005268531.1	XP_005268588.1	1	665
GenBank mRNA	AF061756.1	-	1	720
	BC021190.2	-	1	689	3162118

More Information

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
mesoderm formation
blastocyst development
trophectodermal cell differentiation
heart looping
embryonic heart tube formation
cardiac left ventricle formation
cardiac right ventricle formation
transcription from RNA polymerase II promoter
heart development
embryonic heart tube development
odontogenesis of dentin-containing tooth
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
ventricular cardiac muscle tissue morphogenesis
cardiac septum morphogenesis
mesenchyme development
cartilage morphogenesis
trophoblast giant cell differentiation
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
enzyme binding
identical protein binding
protein homodimerization activity
bHLH transcription factor binding
transcription regulatory region DNA binding
protein heterodimerization activity