53315

• Gene Symbol: Pde2a
• Gene Name: phosphodiesterase 2A, cGMP-stimulated
• Gene Aliases: Pde2, Pde2a2
• Chromosome Location: Chr.1: 166534643 - 166626158 on Build Rnor_6.0
• UniGene ID: Rn.10044
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pde2a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001143847.1	NP_001137319.1	4, 5	502
	NM_001270604.1	NP_001257533.1	4, 5	452
	NM_031079.1	NP_112341.1	3, 4	327
GenBank mRNA	U21101.1	-	3, 4	327

More Information

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cAMP catabolic process
protein targeting to mitochondrion
metabolic process
positive regulation of gene expression
cAMP-mediated signaling
cGMP-mediated signaling
monocyte differentiation
negative regulation of cAMP biosynthetic process
regulation of cGMP metabolic process
negative regulation of protein import into nucleus, translocation
cellular response to drug
cellular response to macrophage colony-stimulating factor stimulus
negative regulation of vascular permeability
positive regulation of vascular permeability
cGMP catabolic process
positive regulation of inflammatory response
establishment of endothelial barrier
cellular response to mechanical stimulus
cellular response to cGMP
cellular response to transforming growth factor beta stimulus
cellular response to granulocyte macrophage colony-stimulating factor stimulus

Function(s)

cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
protein binding
drug binding
cAMP binding
cGMP binding
TPR domain binding
GAF domain binding
protein homodimerization activity
metal ion binding