53411

• Gene Symbol: Pdpk1
• Gene Name: 3-phosphoinositide dependent protein kinase-1
• Gene Aliases: -
• Chromosome Location: Chr.10: 13446373 - 13525248 on Build Rnor_6.0
• UniGene ID: Rn.10905
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pdpk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031081.1	NP_112343.1	4, 5	525
	XM_006246036.2	XP_006246098.1	4, 5	2377
	XM_006246038.2	XP_006246100.1	4, 5	587
GenBank mRNA	Y15748.1	-	4, 5	525

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_001286662, NM_011062, NM_001080773, AY062008, BC146001, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
cell migration
peptidyl-threonine phosphorylation
calcium-mediated signaling
negative regulation of transforming growth factor beta receptor signaling pathway
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
intracellular signal transduction
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
focal adhesion assembly
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
ATP binding
phospholipase activator activity
kinase activity
protein kinase binding
phospholipase binding