53455

• Gene Symbol: Thra
• Gene Name: thyroid hormone receptor alpha
• Gene Aliases: ERBA1, Thra1, c-erbA-1
• Chromosome Location: Chr.10: 86657285 - 86684935 on Build Rnor_6.0
• UniGene ID: Rn.11307
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Thra
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001017960.1	NP_001017960.1	3, 4	563
	NM_031134.2	NP_112396.2	2, 3	431
GenBank mRNA	CB580585.1	-	2, 3	363
	M18028.1	-	3, 4	453
	M31174.1	-		645
	X07409.1	-	1, 2	92
	X12744.1	-	2, 3	95

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_199334, NM_003250, NM_001190918, NM_001190919, J03239, and others.
This siRNA also targets the following transcripts in Mouse: NM_178060, BC046795, AK082121, X51983, X07751, and others.

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

cartilage condensation
ossification
kidney development
liver development
regulation of thyroid hormone mediated signaling pathway
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
brain development
learning or memory
regulation of heart contraction
female courtship behavior
response to cold
hormone-mediated signaling pathway
organ morphogenesis
positive regulation of myotube differentiation
negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
erythrocyte differentiation
lung development
adrenal gland development
intracellular receptor signaling pathway
thyroid gland development
response to nutrient levels
regulation of myeloid cell apoptotic process
response to drug
cytoplasmic sequestering of transcription factor
steroid hormone mediated signaling pathway
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
positive regulation of female receptivity
positive regulation of transcription from RNA polymerase II promoter
digestive tract development
embryonic organ development
regulation of lipid catabolic process
Type I pneumocyte differentiation
negative regulation of DNA-templated transcription, initiation

Function(s)

steroid receptor RNA activator RNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
steroid hormone receptor activity
single-stranded RNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
thyroid hormone receptor activity
transcription factor binding
zinc ion binding
TBP-class protein binding
protein domain specific binding
chromatin DNA binding
protein complex binding
protein homodimerization activity
sequence-specific DNA binding
transcription regulatory region DNA binding
intronic transcription regulatory region DNA binding
protein heterodimerization activity
protein dimerization activity
thyroid hormone binding