5345

• Gene Symbol: HDAC1
• Gene Name: histone deacetylase 1
• Gene Aliases: GON-10, HD1, RPD3, RPD3L1
• Chromosome Location: Chr.1: 32292103 - 32333628 on Build GRCh38
• UniGene ID: Hs.88556
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HDAC1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_004964.2	NP_004955.2	3	257
	XM_011541309.2	XP_011539611.1	3	261
GenBank mRNA	AB451297.1	-	3	194
	AB451430.1	-	3	194
	AK225555.1	-	3	262
	AK296308.1	-	2	147
	AK299241.1	-	3	191
	AK299792.1	-	3	217
	AK313061.1	-	3	260
	AY627042.1	-	3	201
	BC000301.2	-	3	228	2820260
	CR541717.1	-	3	194
	D50405.1	-	3	257
	U50079.1	-	3	304

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053446, NM_001025409, BC107476, BC059156, BC097943.
This siRNA also targets the following transcripts in Mouse: NM_008228, BC092070, BC092285, BC108371, X98207, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
chromatin remodeling
methylation-dependent chromatin silencing
transcription, DNA-templated
protein deacetylation
blood coagulation
positive regulation of cell proliferation
epidermal cell differentiation
negative regulation of gene expression
negative regulation of myotube differentiation
positive regulation of receptor biosynthetic process
viral process
chromatin modification
histone deacetylation
circadian regulation of gene expression
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
ATP-dependent chromatin remodeling
negative regulation of apoptotic process
negative regulation by host of viral transcription
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of androgen receptor signaling pathway
hair follicle placode formation
eyelid development in camera-type eye
fungiform papilla formation
histone H3 deacetylation
histone H4 deacetylation
negative regulation of canonical Wnt signaling pathway
regulation of signal transduction by p53 class mediator
beta-catenin-TCF complex assembly

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
core promoter binding
RNA polymerase II transcription factor binding
RNA polymerase II repressing transcription factor binding
RNA polymerase II transcription corepressor activity
transcription factor activity, sequence-specific DNA binding
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
nucleosomal DNA binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
activating transcription factor binding
histone deacetylase binding
transcription regulatory region DNA binding
protein N-terminus binding
NF-kappaB binding
repressing transcription factor binding