53614

• Gene Symbol: Met
• Gene Name: MET proto-oncogene, receptor tyrosine kinase
• Gene Aliases: Hgfr
• Chromosome Location: Chr.4: 44747191 - 44854628 on Build Rnor_6.0
• UniGene ID: Rn.10617
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Met
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031517.2	NP_113705.1	1	89
	XM_006236129.2	XP_006236191.1	3	505
GenBank mRNA	U65007.1	-	1	89
	X96786.1	-	1	89

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008591, Y00671, AK170560, CJ131939, BC117969, and others.

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
neuron migration
endothelial cell morphogenesis
liver development
placenta development
brain development
muscle organ development
skeletal muscle tissue development
cell aging
lactation
male gonad development
response to wounding
response to acidic pH
positive regulation of gene expression
positive regulation of peptidyl-threonine phosphorylation
negative regulation of peptidyl-threonine phosphorylation
positive regulation of glucose transport
positive regulation of neuron projection development
oligodendrocyte development
response to organic cyclic compound
muscle cell migration
myotube differentiation
peptidyl-tyrosine phosphorylation
central nervous system neuron differentiation
sperm motility
adult behavior
pancreas development
positive regulation of peptidyl-serine phosphorylation
response to drug
glucose homeostasis
response to peptide hormone
positive regulation of DNA replication
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
hepatocyte growth factor receptor signaling pathway
branching morphogenesis of an epithelial tube
positive regulation of dendrite morphogenesis
modulation of synaptic transmission
positive chemotaxis
myoblast proliferation
excitatory postsynaptic potential
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
cellular response to inorganic substance
cellular response to arsenic-containing substance
cellular response to glucose stimulus
cellular response to interleukin-6
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
semaphorin-plexin signaling pathway
negative regulation of hydrogen peroxide-mediated programmed cell death
positive regulation of endothelial cell chemotaxis

Function(s)

protein kinase activity
protein tyrosine kinase activity
hepatocyte growth factor-activated receptor activity
ATP binding
beta-catenin binding
protein phosphatase binding
protein complex binding
phospholipase binding
phosphatidylinositol 3-kinase binding
protein heterodimerization activity