53667

• Gene Symbol: Nrg1
• Gene Name: neuregulin 1
• Gene Aliases: -
• Chromosome Location: Chr.16: 62969988 - 64057434 on Build Rnor_6.0
• UniGene ID: Rn.37438
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nrg1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271121.1	NP_001258050.1	2, 3	629
	NM_001271122.1	NP_001258051.1	2, 3	629
	NM_001271123.1	NP_001258052.1	2, 3	629
	NM_001271124.1	NP_001258053.1	2, 3	629
	NM_001271125.1	NP_001258054.1	2, 3	629
	NM_001271126.1	NP_001258055.1	2, 3	629
	NM_001271127.1	NP_001258056.1	2, 3	629
	NM_001271128.1	NP_001258057.1	2, 3	629
	NM_001271129.1	NP_001258058.1	2, 3	629
	NM_001271130.1	NP_001258059.1	2, 3	699
	NM_031588.2	NP_113776.2	2, 3	629
GenBank mRNA	AF194993.1	-	2, 3	699
	AF194995.1	-	2, 3	532
	AF194996.1	-	2, 3	532
	AF194997.1	-	2, 3	532
	AY973243.1	-		21
	AY973245.1	-	2, 3	297
	AY995221.1	-	2, 3	285
	AY995222.1	-	2, 3	285
	AY995223.1	-	2, 3	285
	M92430.1	-	2, 3	329
	U02315.1	-	2, 3	254
	U02316.1	-	2, 3	629
	U02317.1	-	2, 3	629
	U02318.1	-	2, 3	629
	U02319.1	-	2, 3	629
	U02320.1	-	2, 3	629
	U02321.1	-	2, 3	629
	U02322.1	-	2, 3	629
	U02323.1	-	2, 3	629
	U02324.1	-	2, 3	329

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: AY648976, AK051824.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

MAPK cascade
cell morphogenesis
cardiac conduction system development
ventricular trabecula myocardium morphogenesis
transmembrane receptor protein tyrosine kinase signaling pathway
activation of transmembrane receptor protein tyrosine kinase activity
nervous system development
synapse assembly
peripheral nervous system development
heart development
muscle organ development
locomotory behavior
regulation of blood pressure
cell proliferation
glial cell differentiation
negative regulation of cardiac muscle cell apoptotic process
glucose transport
cell migration
glial cell fate commitment
cell differentiation
positive regulation of cell growth
intracellular signal transduction
ERBB signaling pathway
wound healing
negative regulation of protein catabolic process
myelination
regulation of protein heterodimerization activity
cellular protein complex disassembly
neurotransmitter receptor metabolic process
regulation of cell differentiation
positive regulation of cell adhesion
positive regulation of protein kinase activity
negative regulation of transcription, DNA-templated
positive regulation of Ras protein signal transduction
animal organ development
neuron fate commitment
negative regulation of secretion
positive regulation of protein kinase B signaling
ventricular cardiac muscle cell differentiation
positive regulation of cardiac muscle cell proliferation
cardiac muscle cell myoblast differentiation
endocardial cell differentiation
positive regulation of protein tyrosine kinase activity
positive regulation of calcineurin-NFAT signaling cascade
positive regulation of cardiac muscle cell differentiation
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

transcription cofactor activity
receptor binding
ErbB-2 class receptor binding
growth factor activity
protein tyrosine kinase activator activity
ErbB-3 class receptor binding