53985

• Gene Symbol: Map2k1
• Gene Name: mitogen activated protein kinase kinase 1
• Gene Aliases: Mek1
• Chromosome Location: Chr.8: 69134218 - 69722252 on Build Rnor_6.0
• UniGene ID: Rn.5850
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Map2k1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031643.4	NP_113831.1	2	247
GenBank mRNA	AI603089.1	-	2	247
	BC089772.1	-	2	241	7382030
	D13341.1	-	2	230
	D14591.1	-	2	200
	X62313.1	-	2	237
	Z16415.1	-	2	230

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008927, AK165664, BC051137, L02526, AB041567, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
regulation of vascular smooth muscle contraction
protein phosphorylation
response to oxidative stress
cell cycle arrest
mitotic nuclear division
cell proliferation
negative regulation of cell proliferation
positive regulation of gene expression
peptidyl-tyrosine phosphorylation
neuron differentiation
keratinocyte differentiation
positive regulation of cell migration
melanosome transport
regulation of stress-activated MAPK cascade
positive regulation of transcription elongation from RNA polymerase II promoter
negative regulation of homotypic cell-cell adhesion
peptidyl-tyrosine dephosphorylation
intracellular signal transduction
positive regulation of GTPase activity
positive regulation of cell differentiation
positive regulation of Ras protein signal transduction
vesicle transport along microtubule
Golgi inheritance
response to axon injury
regulation of axon regeneration
neuron projection morphogenesis
cell motility
positive regulation of axonogenesis
protein heterooligomerization
response to glucocorticoid
lung morphogenesis
trachea formation
epithelial cell proliferation involved in lung morphogenesis
placenta blood vessel development
labyrinthine layer development
ERK1 and ERK2 cascade
positive regulation of protein serine/threonine kinase activity
regulation of Golgi inheritance
cellular senescence
regulation of early endosome to late endosome transport

Function(s)

protein serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
receptor signaling protein tyrosine phosphatase activity
protein binding
ATP binding
Ras GTPase binding
protein kinase binding
mitogen-activated protein kinase kinase kinase binding
protein serine/threonine kinase activator activity