54139

• Gene Symbol: Nkx6-1
• Gene Name: NK6 homeobox 1
• Gene Aliases: Nkx6.1, Nkx61, Nkx6a
• Chromosome Location: Chr.14: 9555264 - 9562197 on Build Rnor_6.0
• UniGene ID: Rn.11387
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Nkx6-1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031737.1	NP_113925.1	2	1475
GenBank mRNA	AF004431.1	-	2	1475

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_006168.
This siRNA also targets the following transcripts in Mouse: NM_144955, BC138020, BC138019, AF357883.

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
type B pancreatic cell development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
smoothened signaling pathway
cell proliferation
regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
central nervous system neuron differentiation
neurogenesis
cell differentiation
regulation of axon extension
endocrine pancreas development
positive regulation of insulin secretion
response to nicotine
response to drug
positive regulation of neuron differentiation
negative regulation of glial cell differentiation
positive regulation of glial cell differentiation
oligodendrocyte differentiation
cellular response to cytokine stimulus
cellular response to peptide hormone stimulus
regulation of neuron migration

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding