54509

• Gene Symbol: Src
• Gene Name: SRC proto-oncogene, non-receptor tyrosine kinase
• Gene Aliases: -
• Chromosome Location: Chr.3: 153579324 - 153595643 on Build Rnor_6.0
• UniGene ID: Rn.112600
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Src
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_031977.1	NP_114183.1	3, 4	365
	XM_008762387.1	XP_008760609.1	3, 4	374
	XM_008762388.1	XP_008760610.1	3, 4	411
GenBank mRNA	AF157016.1	-	3, 4	365

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009271, M17031.

Gene Ontology Categories:

Process(es)

protein phosphorylation
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
central nervous system development
cell proliferation
response to mechanical stimulus
response to virus
response to acidic pH
positive regulation of gene expression
regulation of epithelial cell migration
positive regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of glucose metabolic process
positive regulation of smooth muscle cell migration
phosphorylation
single organismal cell-cell adhesion
cell migration
peptidyl-serine phosphorylation
peptidyl-tyrosine phosphorylation
regulation of cell-cell adhesion
intracellular estrogen receptor signaling pathway
forebrain development
response to nutrient levels
positive regulation of protein autophosphorylation
activation of protein kinase B activity
negative regulation of protein homooligomerization
cellular response to insulin stimulus
regulation of intracellular estrogen receptor signaling pathway
adherens junction organization
substrate adhesion-dependent cell spreading
intracellular signal transduction
osteoclast development
cellular response to platelet-derived growth factor stimulus
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
response to drug
response to hydrogen peroxide
positive regulation of apoptotic process
negative regulation of apoptotic process
stress fiber assembly
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of protein binding
positive regulation of MAP kinase activity
positive regulation of phosphatidylinositol 3-kinase activity
transcytosis
innate immune response
bone resorption
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of cell adhesion
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of insulin receptor signaling pathway
protein autophosphorylation
neurotrophin TRK receptor signaling pathway
oogenesis
positive regulation of cytokine secretion
progesterone receptor signaling pathway
positive regulation of protein transport
response to mineralocorticoid
response to electrical stimulus
negative regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of mitochondrial depolarization
uterus development
branching involved in mammary gland duct morphogenesis
regulation of cell projection assembly
positive regulation of ERK1 and ERK2 cascade
response to fatty acid
response to interleukin-1
cellular response to lipopolysaccharide
cellular response to peptide hormone stimulus
cellular response to progesterone stimulus
cellular response to fatty acid
cellular response to hypoxia
cellular response to fluid shear stress
cellular response to transforming growth factor beta stimulus
regulation of podosome assembly
positive regulation of podosome assembly
angiotensin-activated signaling pathway involved in heart process
positive regulation of canonical Wnt signaling pathway
positive regulation of intracellular signal transduction
positive regulation of DNA biosynthetic process
regulation of early endosome to late endosome transport
negative regulation of anoikis
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of intrinsic apoptotic signaling pathway
regulation of caveolin-mediated endocytosis

Function(s)

protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein kinase C binding
receptor binding
insulin receptor binding
protein binding
ATP binding
protein C-terminus binding
kinase activity
enzyme binding
protein kinase binding
protein domain specific binding
heme binding
estrogen receptor binding
protein complex binding
SH2 domain binding
ion channel binding
ephrin receptor binding
cell adhesion molecule binding
phosphoprotein binding
growth factor receptor binding
scaffold protein binding