54631

• Gene Symbol: Gsk3b
• Gene Name: glycogen synthase kinase 3 beta
• Gene Aliases: -
• Chromosome Location: Chr.11: 65060884 - 65209543 on Build Rnor_6.0
• UniGene ID: Rn.10426
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Gsk3b
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_032080.1	NP_114469.1	8	980
	XM_006248373.2	XP_006248435.1	8	1686
	XM_006248374.2	XP_006248436.1	8	1686
	XM_006248375.2	XP_006248437.1	8	1686
	XM_008768745.1	XP_008766967.1	8	1686
GenBank mRNA	FQ231148.1	-	3	248
	FQ233111.1	-	3	248
	X53428.1	-	8	955
	X73653.1	-	8	980

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_019827, AK170965, BC006936, BC060743, AB066114, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

re-entry into mitotic cell cycle
epithelial to mesenchymal transition
positive regulation of cell-matrix adhesion
glycogen metabolic process
regulation of gene expression by genetic imprinting
protein phosphorylation
protein export from nucleus
ER overload response
establishment or maintenance of cell polarity
axonogenesis
myoblast fusion
circadian rhythm
organ morphogenesis
response to lithium ion
negative regulation of cardiac muscle hypertrophy
positive regulation of peptidyl-threonine phosphorylation
regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of neuron maturation
myotube differentiation
Wnt signaling pathway
phosphorylation
cell migration
peptidyl-serine phosphorylation
hippocampus development
establishment of cell polarity
negative regulation of protein complex assembly
positive regulation of protein complex assembly
negative regulation of protein binding
positive regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of microtubule-based process
positive regulation of peptidyl-serine phosphorylation
protein localization to microtubule
intracellular signal transduction
cellular response to interleukin-3
response to drug
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of MAP kinase activity
hypermethylation of CpG island
canonical Wnt signaling pathway involved in positive regulation of apoptotic process
fat cell differentiation
positive regulation of axon extension
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
positive regulation of protein export from nucleus
regulation of neuronal synaptic plasticity
negative regulation of dendrite morphogenesis
negative regulation of NFAT protein import into nucleus
canonical Wnt signaling pathway
superior temporal gyrus development
cellular response to mechanical stimulus
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of stem cell differentiation

Function(s)

RNA polymerase II transcription factor binding
p53 binding
protein kinase activity
protein serine/threonine kinase activity
integrin binding
protein binding
ATP binding
beta-catenin binding
transcription factor binding
kinase activity
protein kinase binding
ubiquitin protein ligase binding
protein kinase A catalytic subunit binding
ionotropic glutamate receptor binding
tau protein binding
tau-protein kinase activity
NF-kappaB binding