5567

• Gene Symbol: APAF1
• Gene Name: apoptotic peptidase activating factor 1
• Gene Aliases: APAF-1, CED4
• Chromosome Location: Chr.12: 98645141 - 98735433 on Build GRCh38
• UniGene ID: Hs.552567
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: APAF1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001160.2	NP_001151.1	26	4626
	NM_013229.2	NP_037361.1	27	4755
	NM_181861.1	NP_863651.1	27	4788
	NM_181868.1	NP_863658.1	26	4659
	NM_181869.1	NP_863659.1	8	2143
GenBank mRNA	AB007873.2	-	26	4178
	AF013263.1	-	26	4626
	BC136531.1	-	27	4359	9020521
	BC136532.1	-	27	4359	9020522
	BC150255.1	-	26	4207	9007183

More Information

Gene Ontology Categories:

Process(es)

response to hypoxia
neural tube closure
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
nervous system development
aging
response to nutrient
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
cardiac muscle cell apoptotic process
cell differentiation
forebrain development
glial cell apoptotic process
regulation of apoptotic process
positive regulation of apoptotic process
protein homooligomerization
neuron apoptotic process
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to transforming growth factor beta stimulus
response to G1 DNA damage checkpoint signaling
intrinsic apoptotic signaling pathway
regulation of apoptotic DNA fragmentation
positive regulation of apoptotic signaling pathway

Function(s)

nucleotide binding
protein binding
ATP binding
cysteine-type endopeptidase activator activity involved in apoptotic process
heat shock protein binding
identical protein binding
ADP binding