5694

• Gene Symbol: HEYL
• Gene Name: hes related family bHLH transcription factor with YRPW motif-like
• Gene Aliases: HESR3, HEY3, HRT3, bHLHb33
• Chromosome Location: Chr.1: 39623431 - 39639676 on Build GRCh38
• UniGene ID: Hs.472566
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HEYL
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_014571.3	NP_055386.1	2, 3	204
	XM_005270745.2	XP_005270802.1	2, 3	258
GenBank mRNA	AF311885.1	-	2, 3	153
	AJ272215.1	-	2, 3	163
	AK300463.1	-	2, 3	163
	AL541019.3	-	2, 3	204
	BC006087.1	-	2, 3	174	2964729

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001107977.
This siRNA also targets the following transcripts in Mouse: NM_013905, AK080822, AJ271868, AB093590, AK028596, and others.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
outflow tract morphogenesis
atrioventricular valve morphogenesis
pulmonary valve morphogenesis
epithelial to mesenchymal transition involved in endocardial cushion formation
endocardial cushion morphogenesis
cardiac ventricle morphogenesis
transcription from RNA polymerase II promoter
Notch signaling pathway
mesenchymal cell development
glomerulus development
skeletal muscle cell differentiation
positive regulation of neuron differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cardiac epithelial to mesenchymal transition
ventricular septum morphogenesis
negative regulation of androgen receptor signaling pathway
cellular response to BMP stimulus
proximal tubule development
negative regulation of androgen receptor activity

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, protein binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription corepressor activity
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
transcription factor binding
microsatellite binding
protein homodimerization activity
protein heterodimerization activity
AF-1 domain binding