5849

• Gene Symbol: TLR7
• Gene Name: toll like receptor 7
• Gene Aliases: TLR7-like
• Chromosome Location: Chr.X: 12867083 - 12890361 on Build GRCh38
• UniGene ID: Hs.659215
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TLR7
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_016562.3	NP_057646.1	3	2029
GenBank mRNA	AB445659.1	-	1	1890
	AF240467.1	-	3	2025
	AF245702.1	-	3	2023
	AK313858.1	-	3	2040
	AY358292.1	-	2	1974
	BC033651.1	-	3	2040	5582912

More Information

Gene Ontology Categories:

Process(es)

microglial cell activation
regulation of protein phosphorylation
toll-like receptor signaling pathway
MyD88-dependent toll-like receptor signaling pathway
inflammatory response
I-kappaB phosphorylation
positive regulation of chemokine production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
toll-like receptor 7 signaling pathway
toll-like receptor 9 signaling pathway
positive regulation of NF-kappaB import into nucleus
positive regulation of interferon-gamma biosynthetic process
innate immune response
positive regulation of interferon-alpha biosynthetic process
positive regulation of interferon-beta biosynthetic process
positive regulation of interleukin-8 biosynthetic process
positive regulation of inflammatory response
defense response to virus
cellular response to mechanical stimulus

Function(s)

double-stranded RNA binding
single-stranded RNA binding
receptor activity
transmembrane signaling receptor activity
drug binding
siRNA binding