59634

• Gene Symbol: Foxa2
• Gene Name: forkhead box A2
• Gene Aliases: Hnf3b
• Chromosome Location: Chr.3: 142383093 - 142387493 on Build Rnor_6.0
• UniGene ID: Rn.10948
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Foxa2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_012743.1	NP_036875.1	3	745
	XM_006235139.2	XP_006235201.1	2	620
	XM_006235140.2	XP_006235202.1	2	872
GenBank mRNA	L09647.1	-	3	745

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010446, CF948812, AB231453, L10409, X74937.

Panther Classification:

Molecular Function -

winged helix/forkhead transcription factor

Gene Ontology Categories:

Process(es)

positive regulation of transcription from RNA polymerase II promoter by glucose
negative regulation of transcription from RNA polymerase II promoter by glucose
in utero embryonic development
ectoderm formation
cell fate specification
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
pattern specification process
adult locomotory behavior
anatomical structure morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
regulation of gene expression
negative regulation of epithelial to mesenchymal transition
chromatin modification
regulation of lipid metabolic process
regulation of steroid metabolic process
cell differentiation in hindbrain
dorsal/ventral neural tube patterning
signal transduction involved in regulation of gene expression
regulation of blood coagulation
lung development
endocrine pancreas development
somite rostral/caudal axis specification
response to insulin
negative regulation of glucokinase activity
positive regulation of embryonic development
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of smoothened signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase III promoter
cell development
anatomical structure formation involved in morphogenesis
neuron fate specification
epithelial tube branching involved in lung morphogenesis
lung epithelial cell differentiation
regulation of insulin secretion involved in cellular response to glucose stimulus
connective tissue development
dopaminergic neuron differentiation
primitive streak formation
positive regulation of gastrulation
negative regulation of detection of glucose

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
kinase binding
protein domain specific binding
sequence-specific DNA binding
transcription regulatory region DNA binding
SMAD binding