60146

• Gene Symbol: Agt
• Gene Name: angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
• Gene Aliases: AI265500, AngI, AngII, Aogen, Serpina8
• Chromosome Location: Chr.8: 124556587 - 124569707 on Build GRCm38
• UniGene ID: Mm.301626
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Agt
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007428.3	NP_031454.3	4	1267
GenBank mRNA	AK005354.1	-	4	1265
	AK018763.1	-	4	1265
	AK139179.1	-	4	1266
	BC019496.1	-	3	1243	4211501
	BC028877.1	-	3	1233	4194190
	BC054387.1	-		1252	6477694

More Information

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

ovarian follicle rupture
blood vessel development
branching involved in ureteric bud morphogenesis
kidney development
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
renin-angiotensin regulation of aldosterone production
regulation of renal output by angiotensin
regulation of heart rate
brain renin-angiotensin system
renal system process
angiotensin-mediated drinking behavior
positive regulation of extracellular matrix constituent secretion
cellular sodium ion homeostasis
cell-matrix adhesion
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
activation of NF-kappaB-inducing kinase activity
excretion
establishment of blood-nerve barrier
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
response to cold
response to salt stress
regulation of gene expression
positive regulation of activation of JAK2 kinase activity
positive regulation of endothelial cell migration
positive regulation of cardiac muscle hypertrophy
positive regulation of gene expression
positive regulation of cholesterol esterification
negative regulation of endopeptidase activity
regulation of norepinephrine secretion
positive regulation of phosphatidylinositol 3-kinase signaling
artery smooth muscle contraction
response to muscle activity involved in regulation of muscle adaptation
negative regulation of angiogenesis
extracellular matrix organization
negative regulation of cell growth
peristalsis
positive regulation of cellular protein metabolic process
positive regulation of superoxide anion generation
positive regulation of peptidyl-serine phosphorylation
negative regulation of tissue remodeling
catenin import into nucleus
regulation of renal sodium excretion
positive regulation of renal sodium excretion
positive regulation of multicellular organism growth
vasoconstriction
vasodilation
hormone metabolic process
drinking behavior
regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
positive regulation of nitric oxide biosynthetic process
positive regulation of fatty acid biosynthetic process
positive regulation of epidermal growth factor receptor signaling pathway
positive regulation of blood pressure
positive regulation of transcription, DNA-templated
positive regulation of vasodilation
positive regulation of organ growth
astrocyte activation
fibroblast proliferation
positive regulation of fibroblast proliferation
regulation of long-term neuronal synaptic plasticity
smooth muscle cell proliferation
cytokine secretion
regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
smooth muscle cell differentiation
negative regulation of neurotrophin TRK receptor signaling pathway
stress-activated MAPK cascade
regulation of calcium ion transport
regulation of transmission of nerve impulse
cell growth involved in cardiac muscle cell development
positive regulation of protein tyrosine kinase activity
ERK1 and ERK2 cascade
uterine smooth muscle contraction
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of protein kinase C activity
regulation of extracellular matrix assembly
positive regulation of membrane hyperpolarization
positive regulation of gap junction assembly
regulation of cardiac conduction
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

serine-type endopeptidase inhibitor activity
hormone activity
sodium channel regulator activity
angiotensin receptor binding
type 1 angiotensin receptor binding
type 2 angiotensin receptor binding