6021

• Gene Symbol: TRAF2
• Gene Name: TNF receptor associated factor 2
• Gene Aliases: MGC:45012, TRAP, TRAP3
• Chromosome Location: Chr.9: 136881776 - 136926615 on Build GRCh38
• UniGene ID: Hs.522506
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TRAF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021138.3	NP_066961.2	9	1088
	XM_011518973.2	XP_011517275.1	10	1392
	XM_011518974.2	XP_011517276.1	9	1993
	XM_011518975.2	XP_011517277.1	10	1320
	XM_011518976.2	XP_011517278.1	10	1361
	XM_011518977.2	XP_011517279.1	9	1081
	XM_011518978.2	XP_011517280.1	9	2502
	XM_017015094.1	XP_016870583.1	9	1136
	XM_017015095.1	XP_016870584.1	9	1846
GenBank mRNA	AK054686.1	-	8	913
	AK289722.1	-	10	1204
	AK294607.1	-	9	947
	AK298370.1	-	9	1052
	BC032410.1	-	8	1074	5216790
	BC033810.1	-	9	1076	5182942
	BC043492.1	-	9	1088	5767794
	BC064662.1	-	8	1083	6528158
	BX538160.1	-	8	1030

More Information

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of T cell cytokine production
protein complex assembly
activation of cysteine-type endopeptidase activity involved in apoptotic process
signal transduction
I-kappaB kinase/NF-kappaB signaling
activation of NF-kappaB-inducing kinase activity
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
protein catabolic process
positive regulation of interleukin-2 production
tumor necrosis factor-mediated signaling pathway
negative regulation of glial cell apoptotic process
response to endoplasmic reticulum stress
regulation of apoptotic process
positive regulation of JUN kinase activity
cellular protein complex assembly
positive regulation of T cell activation
regulation of immunoglobulin secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein heterooligomerization
protein autoubiquitination
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
protein homotrimerization
protein K63-linked ubiquitination
death-inducing signaling complex assembly
cellular response to nitric oxide
positive regulation of protein homodimerization activity
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
programmed necrotic cell death
negative regulation of neuron death
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of I-kappaB phosphorylation
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

ubiquitin-protein transferase activity
signal transducer activity
tumor necrosis factor receptor binding
CD40 receptor binding
protein binding
zinc ion binding
ligase activity
enzyme binding
protein kinase binding
protein phosphatase binding
mitogen-activated protein kinase kinase kinase binding
ubiquitin protein ligase binding
thioesterase binding
protein complex binding
identical protein binding
sphingolipid binding