60653

• Gene Symbol: Chek1
• Gene Name: checkpoint kinase 1
• Gene Aliases: C85740, Chk1, rad27
• Chromosome Location: Chr.9: 36708482 - 36726658 on Build GRCm38
• UniGene ID: Mm.16753
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Chek1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_007691.5	NP_031717.2	3	350
GenBank mRNA	AF016583.1	-	2	259
	AK011258.1	-	3	294
	AK033179.1	-	3	320
	AK045336.1	-	3	292
	AK166675.1	-	3	351
	BC053394.1	-	3	286
	BC064445.1	-	2	750
	BC100386.1	-	2	425	30481390

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
DNA repair
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
cell cycle
regulation of gene expression
regulation of double-strand break repair via homologous recombination
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
negative regulation of G2/M transition of mitotic cell cycle
phosphorylation
peptidyl-threonine phosphorylation
G2 DNA damage checkpoint
histone H3-T11 phosphorylation
regulation of cell proliferation
negative regulation of mitotic nuclear division
regulation of mitotic centrosome separation
chromatin-mediated maintenance of transcription
negative regulation of DNA biosynthetic process
regulation of histone H3-K9 acetylation

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
histone kinase activity (H3-T11 specific)